The largest number of discrepancies was found while scanning for DME, and FA was more sensitive than TD-OCT for this condition: 42.2% of eyes showed discrepancy. Similarly, TD-OCT detected both intraretinal and subretinal fluid in 1.17% eyes, while FA failed to detect any fluid. In 3.86% of eyes, they found that FA showed dye leakage in the macular area, but TD-OCT showed normal foveal contour. Kozak et al, 1 in analyzing discrepancy rates between intravenous FA and time-domain OCT (TD-OCT) for diagnosing macular edema, found that the sensitivity of FA and OCT was 98.7% and 96.1%, respectively. Both are useful, and often complimentary, in the diagnosis and management of a variety of retinal disorders, such as age-related macular degeneration (AMD), idiopathic juxtafoveolar retinal telangiectasis (IJRT), myopic choroidal neovascularization (CNV), uveitic cystoid macular edema (CME), diabetic macular edema (DME), central serous chorioretinopathy (CSC), and vitreomacular interface disorder.Įach modality has unique strengths and weaknesses. Both diagnostic tools depend heavily upon patient cooperation.
#Normal retina fluorescien angiography registration
Registration of OCT scans helps clinicians properly assess patients during follow-up visits. Optical coherence tomography is objective and is not so much affected by pupil size or media clarity. Fluorescein angiography is invasive, nonquantitative, and subjective, with limited use for patients with small pupils or insufficient media clarity. This article compares the 2 technologies in various clinical situations.įluorescein angiography provides retinal circulation details, and OCT offers high-quality anatomic images. These investigative modalities complement each other, and many situations require both imaging methods to make the correct diagnosis and treatment plan. Fluorescein angiography (FA) and optical coherence tomography (OCT) scans are important tools used in the examination and management of retinal diseases.
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